Générique Emflaza

Marque(s): Defnalone

Fabricant: Lupin

Diseases: Duchenne Muscular Dystrophy / DMD

Emflaza est un corticostéroïde indiqué pour le traitement de la dystrophie musculaire de Duchenne (DMD) chez les patients âgés de 5 ans et plus.
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6mg × 10 tablet € 27.11Par comprimé € 2.71 € 2.71 Ajouter au panier
6mg × 20 tablet € 45.21Par comprimé € 2.26 € 2.26 € 9.01 Ajouter au panier
6mg × 30 tablet € 54.27Par comprimé € 1.81 € 1.81 € 27.07 Ajouter au panier
6mg × 60 tablet € 67.84Par comprimé € 1.13 € 1.13 € 94.82 Ajouter au panier
6mg × 90 tablet € 81.42Par comprimé € 0.90 € 0.90 € 162.57 Ajouter au panier
6mg × 120 tablet € 90.47Par comprimé € 0.75 € 0.75 € 234.85 Ajouter au panier
6mg × 180 tablet € 117.63Par comprimé € 0.65 € 0.65 € 370.36 Ajouter au panier
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24mg × 12 tablet € 63.32Par comprimé € 5.28 € 5.28 Ajouter au panier
24mg × 24 tablet € 117.63Par comprimé € 4.90 € 4.90 € 9.01 Ajouter au panier
24mg × 36 tablet Free AirMail shipping € 171.94Par comprimé € 4.78 € 4.78 € 18.01 Ajouter au panier
24mg × 60 tablet Free AirMail shipping € 271.51Par comprimé € 4.53 € 4.53 € 45.08 Ajouter au panier
24mg × 90 tablet Free AirMail shipping € 393.72Par comprimé € 4.37 € 4.37 € 81.17 Ajouter au panier
24mg × 120 tablet Free AirMail shipping € 497.81Par comprimé € 4.15 € 4.15 € 135.37 Ajouter au panier
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30mg × 12 tablet € 81.42Par comprimé € 6.79 € 6.79 Ajouter au panier
30mg × 24 tablet Free AirMail shipping € 144.79Par comprimé € 6.03 € 6.03 € 18.06 Ajouter au panier
30mg × 36 tablet Free AirMail shipping € 208.15Par comprimé € 5.78 € 5.78 € 36.12 Ajouter au panier
30mg × 60 tablet Free AirMail shipping € 325.83Par comprimé € 5.43 € 5.43 € 81.29 Ajouter au panier
30mg × 90 tablet Free AirMail shipping € 452.55Par comprimé € 5.03 € 5.03 € 158.12 Ajouter au panier

Deflazacort tablets

What is this medicine?

Deflazacort a corticosteroid indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients 5 years of age and older.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

  • Hypersensitivity to deflazacort;
  • Alterations in Endocrine Function: Hypothalamic-pituitary-adrenal axis suppression, Cushing’s syndrome, and hyperglycemia;
  • Immunosuppression and Increased Risk of Infection: Increased risk of new, exacerbation, dissemination, or reactivation of latent infections, which can be severe and at times fatal;
  • Alterations in Cardiovascular/Renal Function: elevated blood pressure and sodium, and for decreased potassium level;
  • Gastrointestinal Perforation: GI disorders;
  • Behavioral and Mood Disturbances: euphoria, insomnia, mood swings, personality changes, severe depression, and psychosis;
  • Effects on Bones: decreases in bone mineral density;
  • Serious Skin Rashes;
  • Ophthalmic Effects: May include cataracts, infections, and glaucoma;
  • Vaccination: Do not administer live or live attenuated vaccines to patients receiving immunosuppressive doses of corticosteroids.

How should I use this medicine?

The recommended once-daily dosage is approximately 0.9 mg/kg/day administered orally. Discontinue gradually when administered for more than a few day..

What may interact with this medicine?

  • Moderate or strong CYP3A4 inhibitors: Give one third of the recommended dosage;
  • Avoid use of moderate or strong CYP3A4 inducers, as they may reduce efficacy.

What side effects may I notice from this medicine?

The most common adverse reactions are Cushingoid appearance, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, and nasopharyngitis.

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